Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479790 | 0.98 | CKS1B (0.37) | ENPP2MAPTMEN1KMT2ATSHR | |
| SCHEMBL31479700 | 0.93 | RET (0.37) | ENPP2MAPTMEN1KMT2ATSHR | |
| SCHEMBL31479143 | 0.92 | MAPT (0.40) | ENPP2MAPTMEN1KMT2ATSHR | |
| SCHEMBL31479674 | 0.91 | ENPP2 (0.37) | ENPP2MAPTMEN1KMT2ATSHR | |
| SCHEMBL31479681 | 0.91 | MEN1 (0.35) | MEN1KMT2ARETGPR119PIK3CA | |
| SCHEMBL31479380 | 0.89 | PREP (0.38) | ENPP2MAPTMEN1KMT2ARET | |
| SCHEMBL31479015 | 0.88 | MAPT (0.38) | MAPTMEN1KMT2ASMN1; SMN2GPR119 | |
| SCHEMBL31479366 | 0.87 | ENPP2 (0.39) | ENPP2MAPTMEN1KMT2ATSHR | |
| SCHEMBL31479892 | 0.87 | GPBAR1 (0.38) | SMN1; SMN2GPR119NR1H2NR1H3 | |
| SCHEMBL31479517 | 0.86 | SMN1; SMN2 (0.42) | MAPTMEN1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |