Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 8/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479282 | 0.88 | PREP (0.38) | ENPP2P2RX7MAPTGPR119 | |
| SCHEMBL31478993 | 0.87 | ENPP2 (0.37) | ENPP2MAPTGPR119PDK2MEN1 | |
| SCHEMBL31479368 | 0.87 | HCRTR1 (0.34) | IDO1TDO2IDO2 | |
| SCHEMBL31479007 | 0.87 | GPBAR1 (0.37) | ENPP2GPR119MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31479790 | 0.85 | CKS1B (0.37) | ENPP2MAPTGPR119SUV39H2PDK2 | |
| SCHEMBL31479143 | 0.84 | MAPT (0.40) | ENPP2MAPTGPR119PDK2MEN1 | |
| SCHEMBL31479674 | 0.83 | ENPP2 (0.37) | ENPP2MAPTGPR119PDK2MEN1 | |
| SCHEMBL31479463 | 0.83 | MEN1 (0.39) | MAPTMEN1KMT2A | |
| SCHEMBL31479996 | 0.83 | GPR119 (0.37) | ENPP2MAPTGPR119IDO1PDK2 | |
| SCHEMBL31479700 | 0.81 | RET (0.37) | ENPP2MAPTGPR119PDK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |