Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSC | P53634 | 11/20 | 0.33 |
| ▸ | CTSK | P43235 | 6/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479859 | 0.88 | MEN1 (0.37) | MEN1KMT2ACTSCCTSKCCKAR | |
| SCHEMBL31479652 | 0.85 | MEN1 (0.41) | MEN1KMT2ACTSC | |
| SCHEMBL31479542 | 0.84 | HDAC3 (0.37) | — | |
| SCHEMBL31479196 | 0.83 | MEN1 (0.40) | MEN1KMT2ACTSCCTSK | |
| SCHEMBL31479621 | 0.82 | ENPP2 (0.37) | MEN1KMT2A | |
| SCHEMBL31479751 | 0.82 | PREP (0.38) | CCKAR | |
| SCHEMBL31479391 | 0.82 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL31479541 | 0.81 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL31478963 | 0.80 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL31479481 | 0.76 | GPBAR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |