SCHEMBL31479751

SCHEMBL31479751

CCN(C(=O)C(C)C)c1cc(F)ccc1-c1cc(N2CCN(C(=O)[C@H]3C4CCC(CC4)N3C(=O)OC(C)(C)C)CC2)cn2c(C)ncc12

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PREP P48147 4/20 0.38
GPR119 Q8TDV5 3/20 0.31
CCKAR P32238 1/20 0.31
ENPP2 Q13822 1/20 0.31
MC4R P32245 1/20 0.31
LMNA P02545 1/20 0.31
RET P07949 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479250 0.89 PREP (0.39) PREPGPR119CCKARENPP2MC4R
SCHEMBL31479621 0.89 ENPP2 (0.37) GPR119ENPP2LMNARETMAPT
SCHEMBL31479380 0.86 PREP (0.38) PREPGPR119ENPP2MC4RLMNA
SCHEMBL31478999 0.85 PREP (0.40) PREPGPR119MAPT
SCHEMBL31479454 0.83 PREP (0.38) PREPGPR119MC4RLMNARET
SCHEMBL31479921 0.83 PREP (0.39) PREPGPR119LMNAMAPT
SCHEMBL31479264 0.82 PREP (0.41) PREPGPR119LMNAMAPT
SCHEMBL31479111 0.82 MEN1 (0.36) CCKAR
SCHEMBL31479706 0.80 PREP (0.38) PREPGPR119LMNARETMAPT
SCHEMBL31479542 0.78 HDAC3 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed