Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479066 | 1.00 | GPR119 (0.39) | GPR119SMN1; SMN2PDE4BPOLBGPBAR1 | |
| SCHEMBL31479646 | 1.00 | GPR119 (0.39) | GPR119SMN1; SMN2PDE4BPOLBGPBAR1 | |
| SCHEMBL31479791 | 0.97 | ALOX5AP (0.39) | GPR119SMN1; SMN2PDE4BPOLBGPBAR1 | |
| SCHEMBL31479405 | 0.94 | GPBAR1 (0.41) | GPR119SMN1; SMN2POLBGPBAR1TP53 | |
| SCHEMBL31479320 | 0.94 | GPR119 (0.39) | GPR119SMN1; SMN2POLBGPBAR1TP53 | |
| SCHEMBL31479837 | 0.94 | GPR119 (0.39) | GPR119SMN1; SMN2POLBGPBAR1TP53 | |
| SCHEMBL31479262 | 0.94 | GPR119 (0.39) | GPR119SMN1; SMN2POLBGPBAR1TP53 | |
| SCHEMBL31479852 | 0.88 | GPBAR1 (0.40) | GPR119SMN1; SMN2POLBGPBAR1TP53 | |
| SCHEMBL31479742 | 0.88 | GPR119 (0.38) | GPR119SMN1; SMN2TP53ALOX5APFEN1 | |
| SCHEMBL31479005 | 0.88 | GPR119 (0.38) | GPR119SMN1; SMN2TP53ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |