Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479066 | 0.94 | GPR119 (0.39) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479646 | 0.94 | GPR119 (0.39) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479136 | 0.94 | GPR119 (0.39) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479791 | 0.94 | ALOX5AP (0.39) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479852 | 0.93 | GPBAR1 (0.40) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479195 | 0.88 | PLK1 (0.36) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479262 | 0.88 | GPR119 (0.39) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479837 | 0.88 | GPR119 (0.39) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479320 | 0.88 | GPR119 (0.39) | GPBAR1ALOX5APFEN1SMN1; SMN2GPR119 | |
| SCHEMBL31479750 | 0.85 | SMN1; SMN2 (0.45) | GPBAR1ALOX5APFEN1SMN1; SMN2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |