Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31478953 | 0.96 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBTP53MAPTMEN1 | |
| SCHEMBL31479750 | 0.93 | SMN1; SMN2 (0.45) | SMN1; SMN2ALOX5APFEN1POLBTP53 | |
| SCHEMBL31479246 | 0.90 | POLB (0.41) | SMN1; SMN2ALOX5APFEN1POLBHPGDS | |
| SCHEMBL31479791 | 0.86 | ALOX5AP (0.39) | SMN1; SMN2ALOX5APFEN1POLBHPGDS | |
| SCHEMBL31479761 | 0.86 | TP53 (0.45) | SMN1; SMN2POLBTP53MEN1HPGD | |
| SCHEMBL31479262 | 0.83 | GPR119 (0.39) | SMN1; SMN2ALOX5APFEN1POLBTP53 | |
| SCHEMBL31479320 | 0.83 | GPR119 (0.39) | SMN1; SMN2ALOX5APFEN1POLBTP53 | |
| SCHEMBL31479837 | 0.83 | GPR119 (0.39) | SMN1; SMN2ALOX5APFEN1POLBTP53 | |
| SCHEMBL31479136 | 0.82 | GPR119 (0.39) | SMN1; SMN2ALOX5APFEN1POLBTP53 | |
| SCHEMBL31479724 | 0.82 | POLB (0.40) | SMN1; SMN2ALOX5APFEN1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |