Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 12/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479689 | 0.83 | HCRTR1 (0.40) | HCRTR1HCRTR2MEN1KMT2ACASP3 | |
| SCHEMBL31479982 | 0.78 | HCRTR1 (0.42) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479832 | 0.77 | HCRTR1 (0.40) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479205 | 0.76 | HCRTR1 (0.40) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479308 | 0.75 | HCRTR1 (0.39) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479169 | 0.74 | HCRTR1 (0.39) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479558 | 0.73 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL20846978 | 0.72 | HCRTR1 (0.40) | HCRTR1HCRTR2CASP3 | |
| SCHEMBL31619787 | 0.71 | KEAP1 (0.50) | HCRTR1HCRTR2CASP3 | |
| SCHEMBL31479160 | 0.70 | HCRTR1 (0.41) | HCRTR1HCRTR2MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |