Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479286 | 0.87 | HCRTR1 (0.40) | HCRTR1HCRTR2RORCRORB | |
| SCHEMBL31479558 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2PSEN1PSEN2APH1B | |
| SCHEMBL31479873 | 0.84 | HCRTR1 (0.41) | HCRTR1HCRTR2PSEN1PSEN2APH1B | |
| SCHEMBL31479434 | 0.83 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL31478959 | 0.82 | HCRTR1 (0.39) | HCRTR1HCRTR2SCN9ARORCRORB | |
| SCHEMBL31479023 | 0.81 | HCRTR1 (0.39) | HCRTR1HCRTR2PSEN1PSEN2APH1B | |
| SCHEMBL31479844 | 0.80 | HCRTR1 (0.38) | HCRTR1HCRTR2PSEN1PSEN2APH1B | |
| SCHEMBL31479263 | 0.78 | HCRTR1 (0.41) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479626 | 0.71 | F2R (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL31619787 | 0.71 | KEAP1 (0.50) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |