Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | MAP2 | P11137 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479366 | 0.87 | ENPP2 (0.39) | IDO1TDO2IDO2 | |
| SCHEMBL31479226 | 0.85 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL31479296 | 0.85 | HCRTR1 (0.36) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479463 | 0.84 | MEN1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL31479662 | 0.83 | HCRTR1 (0.35) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479725 | 0.81 | HCRTR1 (0.36) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31478997 | 0.79 | HCRTR1 (0.36) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479007 | 0.78 | GPBAR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL31479549 | 0.77 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL31478968 | 0.77 | HCRTR1 (0.36) | HCRTR1HCRTR2HTR2COPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |