Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479603 | 0.91 | MEN1 (0.54) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479487 | 0.91 | MEN1 (0.35) | MEN1KMT2AKCNH2 | |
| SCHEMBL31478983 | 0.89 | MEN1 (0.35) | MEN1KMT2AKCNH2 | |
| SCHEMBL31479440 | 0.86 | KCNH2 (0.42) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479214 | 0.86 | KCNH2 (0.42) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479046 | 0.86 | KCNH2 (0.42) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479667 | 0.82 | MEN1 (0.43) | MEN1KMT2AKCNH2HTR2A | |
| SCHEMBL31479712 | 0.80 | MEN1 (0.44) | MEN1KMT2AKCNH2DRD3 | |
| SCHEMBL31479536 | 0.77 | JAK2 (0.34) | MEN1KMT2AKCNH2 | |
| SCHEMBL31479564 | 0.76 | HCRTR1 (0.34) | MEN1KMT2AKCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |