Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 9/20 | 0.34 |
| ▸ | JAK1 | P23458 | 8/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479345 | 0.92 | JAK2 (0.34) | JAK2JAK1JAK3PTK2RORC | |
| SCHEMBL31479730 | 0.89 | ALOX5AP (0.36) | JAK2JAK1JAK3PTK2GPR119 | |
| SCHEMBL31479712 | 0.83 | MEN1 (0.44) | JAK2JAK1MEN1KMT2AKCNH2 | |
| SCHEMBL31479578 | 0.83 | RORC (0.34) | JAK2JAK1RORCGPR119MEN1 | |
| SCHEMBL31478983 | 0.83 | MEN1 (0.35) | MEN1KMT2AKCNH2ALOX5APFEN1 | |
| SCHEMBL31479852 | 0.82 | GPBAR1 (0.40) | JAK2JAK3PTK2GPR119ALOX5AP | |
| SCHEMBL31479262 | 0.81 | GPR119 (0.39) | GPR119ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL31479320 | 0.81 | GPR119 (0.39) | GPR119ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL31479837 | 0.81 | GPR119 (0.39) | GPR119ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL31479564 | 0.81 | HCRTR1 (0.34) | MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |