SCHEMBL31479564

SCHEMBL31479564

CCN(C(=O)c1cc(F)ccc1-c1cc(C2(F)CCNC2)cc2c1cnn2C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 7/20 0.34
HCRTR2 O43614 7/20 0.34
SYK P43405 1/20 0.33
PIM1 P11309 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KCNH2 Q12809 1/20 0.31
CNR2 P34972 1/20 0.31
DRD2 P14416 1/20 0.31
HTR2A P28223 1/20 0.31
HTR7 P34969 1/20 0.31
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479437 0.87 HCRTR1 (0.37) HCRTR1HCRTR2SYKMEN1KMT2A
SCHEMBL31479536 0.81 JAK2 (0.34) MEN1KMT2AKCNH2
SCHEMBL31479666 0.81 HCRTR1 (0.35) HCRTR1HCRTR2MEN1KMT2AKCNH2
SCHEMBL31479670 0.80 HCRTR1 (0.36) HCRTR1HCRTR2MEN1KMT2AKCNH2
SCHEMBL31479308 0.80 HCRTR1 (0.39) HCRTR1HCRTR2MEN1KMT2AKCNH2
SCHEMBL31479667 0.79 MEN1 (0.43) HCRTR1HCRTR2MEN1KMT2AKCNH2
SCHEMBL31479110 0.79 SLC6A2 (0.35) HCRTR1HCRTR2HTR2AHTR7AKT1
SCHEMBL31479544 0.79 SLC6A2 (0.35) HCRTR1HCRTR2HTR2AHTR7AKT1
SCHEMBL31479460 0.79 SLC6A2 (0.35) HCRTR1HCRTR2HTR2AHTR7AKT1
SCHEMBL31479324 0.76 HCRTR1 (0.35) HCRTR1HCRTR2SYKMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed