Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479564 | 0.87 | HCRTR1 (0.34) | HCRTR1HCRTR2KCNH2MEN1KMT2A | |
| SCHEMBL31479730 | 0.84 | ALOX5AP (0.36) | HCRTR1HCRTR2KCNH2MEN1KMT2A | |
| SCHEMBL31479670 | 0.82 | HCRTR1 (0.36) | HCRTR1HCRTR2KCNH2MEN1KMT2A | |
| SCHEMBL31479308 | 0.82 | HCRTR1 (0.39) | HCRTR1HCRTR2KCNH2MEN1KMT2A | |
| SCHEMBL31479345 | 0.82 | JAK2 (0.34) | HCRTR1HCRTR2KCNH2MEN1KMT2A | |
| SCHEMBL31479460 | 0.80 | SLC6A2 (0.35) | HCRTR1HCRTR2HTR2AHTR7TRPV1 | |
| SCHEMBL31479110 | 0.80 | SLC6A2 (0.35) | HCRTR1HCRTR2HTR2AHTR7TRPV1 | |
| SCHEMBL31479544 | 0.80 | SLC6A2 (0.35) | HCRTR1HCRTR2HTR2AHTR7TRPV1 | |
| SCHEMBL31479324 | 0.78 | HCRTR1 (0.35) | HCRTR1HCRTR2KCNH2MEN1KMT2A | |
| SCHEMBL31479897 | 0.77 | HCRTR1 (0.34) | HCRTR1HCRTR2KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |