Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479345 | 0.94 | JAK2 (0.34) | ALOX5APFEN1HCRTR1HCRTR2JAK2 | |
| SCHEMBL31479536 | 0.89 | JAK2 (0.34) | ALOX5APFEN1JAK2JAK3PTK2 | |
| SCHEMBL31479437 | 0.84 | HCRTR1 (0.37) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479852 | 0.84 | GPBAR1 (0.40) | ALOX5APFEN1JAK2JAK3PTK2 | |
| SCHEMBL31479566 | 0.83 | MEN1 (0.42) | ALOX5APFEN1JAK2MEN1KMT2A | |
| SCHEMBL31479353 | 0.83 | ALOX5AP (0.35) | ALOX5APFEN1HCRTR1HCRTR2JAK2 | |
| SCHEMBL31479737 | 0.83 | CDK9 (0.36) | ALOX5APFEN1HCRTR1HCRTR2JAK2 | |
| SCHEMBL31479837 | 0.82 | GPR119 (0.39) | ALOX5APFEN1GPR119SMN1; SMN2 | |
| SCHEMBL31479320 | 0.82 | GPR119 (0.39) | ALOX5APFEN1GPR119SMN1; SMN2 | |
| SCHEMBL31479262 | 0.82 | GPR119 (0.39) | ALOX5APFEN1GPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |