Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479001 | 0.82 | TSHR (0.36) | TSHRNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31479832 | 0.81 | HCRTR1 (0.40) | GRIN2BMEN1KMT2A | |
| SCHEMBL31479031 | 0.78 | GRIN2B (0.35) | GRIN2B | |
| SCHEMBL31479829 | 0.77 | POLB (0.40) | SMN1; SMN2LMNAPOLBALDH1A1GAA | |
| SCHEMBL31479060 | 0.77 | TP53 (0.40) | TSHRSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL31479481 | 0.75 | GPBAR1 (0.34) | GRIN2B | |
| SCHEMBL31479010 | 0.75 | CDK9 (0.38) | SMN1; SMN2LMNAPOLBALDH1A1GAA | |
| SCHEMBL31479089 | 0.75 | TSHR (0.41) | TSHRNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31479237 | 0.75 | POLB (0.45) | SMN1; SMN2LMNAPOLBALDH1A1GAA | |
| SCHEMBL31479407 | 0.75 | POLB (0.45) | SMN1; SMN2LMNAPOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |