Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479857 | 0.90 | KCNH2 (0.39) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479174 | 0.88 | PDE6D (0.37) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479634 | 0.85 | MEN1 (0.35) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479528 | 0.84 | GPR119 (0.41) | — | |
| SCHEMBL31479477 | 0.82 | GPR119 (0.40) | GPBAR1 | |
| SCHEMBL31479129 | 0.82 | GPR119 (0.40) | GPBAR1 | |
| SCHEMBL31479929 | 0.82 | GPR119 (0.40) | GPBAR1 | |
| SCHEMBL31479415 | 0.82 | MEN1 (0.41) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479249 | 0.82 | HCRTR1 (0.35) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31478997 | 0.79 | HCRTR1 (0.36) | HCRTR1HCRTR2MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |