Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479477 | 1.00 | GPR119 (0.40) | GPR119SMN1; SMN2POLBTRPV3BRD3 | |
| SCHEMBL31479929 | 1.00 | GPR119 (0.40) | GPR119SMN1; SMN2POLBTRPV3BRD3 | |
| SCHEMBL31479528 | 0.96 | GPR119 (0.41) | GPR119SMN1; SMN2POLB | |
| SCHEMBL31479920 | 0.89 | PREP (0.40) | GPR119SMN1; SMN2POLBGPBAR1 | |
| SCHEMBL31479691 | 0.89 | GPBAR1 (0.32) | GPR119SMN1; SMN2POLBGPBAR1 | |
| SCHEMBL31479100 | 0.87 | GPR119 (0.39) | GPR119SMN1; SMN2POLBTRPV3BRD3 | |
| SCHEMBL31479516 | 0.87 | GPR119 (0.39) | GPR119SMN1; SMN2POLBTRPV3BRD3 | |
| SCHEMBL31479241 | 0.86 | ENPP2 (0.33) | GPR119SMN1; SMN2 | |
| SCHEMBL31479634 | 0.84 | MEN1 (0.35) | — | |
| SCHEMBL31479996 | 0.84 | GPR119 (0.37) | GPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |