Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479976 | 0.91 | MEN1 (0.43) | MEN1KMT2AKCNH2CNR2HCRTR1 | |
| SCHEMBL31478975 | 0.89 | MEN1 (0.45) | MEN1KMT2AKCNH2CNR2CRHR1 | |
| SCHEMBL31479611 | 0.86 | MEN1 (0.55) | MEN1KMT2AKCNH2CNR2HTR2A | |
| SCHEMBL31479701 | 0.85 | MEN1 (0.50) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479807 | 0.85 | MEN1 (0.50) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479603 | 0.84 | MEN1 (0.54) | MEN1KMT2AKCNH2CNR2HTR2A | |
| SCHEMBL31479949 | 0.83 | MEN1 (0.53) | MEN1KMT2AKCNH2CNR2HTR2A | |
| SCHEMBL31479336 | 0.81 | MEN1 (0.47) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479290 | 0.80 | MEN1 (0.47) | MEN1KMT2AKCNH2HCRTR1HCRTR2 | |
| SCHEMBL31478741 | 0.80 | MEN1 (0.53) | MEN1KMT2AKCNH2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |