SCHEMBL31478741 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	2/20	0.53

▸	KMT2A	Q03164	2/20	0.53

▸	KCNH2	Q12809	1/20	0.53

▸	HTR2A	P28223	3/20	0.38

▸	DRD3	P35462	2/20	0.38

▸	HCRTR1	O43613	3/20	0.34

▸	HCRTR2	O43614	3/20	0.34

▸	CRHR1	P34998	1/20	0.33

▸	CRHR2	Q13324	1/20	0.33

▸	ACKR3	P25106	5/20	0.33

▸	MELK	Q14680	3/20	0.32

▸	CHRM2	P08172	1/20	0.32

▸	DRD2	P14416	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31479807	0.85	MEN1 (0.50)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479701	0.83	MEN1 (0.50)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31478700	0.81	HCRTR1 (0.38)	MEN1KMT2AKCNH2HCRTR1HCRTR2
SCHEMBL31479389	0.81	MEN1 (0.49)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479383	0.80	MEN1 (0.50)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479242	0.80	MEN1 (0.45)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479610	0.80	MEN1 (0.51)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479645	0.80	MEN1 (0.51)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479270	0.80	MEN1 (0.47)	MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31478734	0.79	GPR119 (0.40)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025067111-A1	MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION	苏州必扬医药科技有限公司	2025-04-03	—	—	WO	disclosed