Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479415 | 0.90 | MEN1 (0.41) | MEN1KMT2AKCNH2CNR2HCRTR1 | |
| SCHEMBL31479427 | 0.88 | MEN1 (0.42) | MEN1KMT2AKCNH2DRD3CNR2 | |
| SCHEMBL31479645 | 0.85 | MEN1 (0.51) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479610 | 0.85 | MEN1 (0.51) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479853 | 0.83 | MEN1 (0.55) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479603 | 0.80 | MEN1 (0.54) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479890 | 0.80 | HCRTR1 (0.36) | MEN1KMT2AKCNH2CNR2HCRTR1 | |
| SCHEMBL31479611 | 0.78 | MEN1 (0.55) | MEN1KMT2AKCNH2HTR2ADRD3 | |
| SCHEMBL31479928 | 0.78 | ALOX5AP (0.35) | MEN1KMT2AKCNH2CNR2HCRTR1 | |
| SCHEMBL31479148 | 0.77 | MEN1 (0.42) | MEN1KMT2AKCNH2CNR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |