Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PDE1A | P54750 | 3/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29176019 | 0.83 | TDP1 (0.39) | ALDH1A1PDE1APDE1BPDE1CHTT | |
| SCHEMBL14909505 | 0.80 | TDP1 (0.44) | ALDH1A1PDE9AMEN1KMT2AHTT | |
| SCHEMBL30448079 | 0.77 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL21273360 | 0.77 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29176051 | 0.75 | MAPT (0.34) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL16898982 | 0.75 | MAPT (0.38) | MAPTALDH1A1CYP19A1GPR119MAPK1 | |
| SCHEMBL25269473 | 0.75 | SCD (0.37) | PDE1APDE1BPDE1CPDE9A | |
| SCHEMBL25428025 | 0.73 | CREBBP (0.35) | MAPTALDH1A1PDE1APDE1BPDE1C | |
| SCHEMBL31339761 | 0.73 | HTT (0.40) | MAPTALDH1A1CYP19A1HTTCYP1A2 | |
| SCHEMBL23389349 | 0.70 | GRM1 (0.42) | ALDH1A1PDE1APDE1BPDE1CMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082460-A1 | DIACYLGLYCEROL KINASE INHIBITOR COMPOUND AND USE THEREOF | 上海先祥医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |