Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 3/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479973 | 0.83 | MAPT (0.36) | TDP1VCAM1PDE1APDE1BPDE1C | |
| SCHEMBL14909505 | 0.80 | TDP1 (0.44) | TDP1LMNAHTTALDH1A1 | |
| SCHEMBL23536385 | 0.77 | TDP1 (0.43) | TDP1HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL26921917 | 0.75 | PDE4D (0.36) | PDE4DPDE1APDE1BPDE1CGRM1 | |
| SCHEMBL2517797 | 0.74 | PKM (0.39) | TDP1VCAM1NPBWR1MCHR1LMNA | |
| SCHEMBL29176051 | 0.73 | MAPT (0.34) | TDP1LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23389349 | 0.70 | GRM1 (0.42) | TDP1PDE1APDE1BPDE1CALDH1A1 | |
| SCHEMBL16898982 | 0.69 | MAPT (0.38) | ALDH1A1PKM | |
| SCHEMBL31319707 | 0.69 | PKM (0.38) | VCAM1NPBWR1MCHR1GSRTXNRD1 | |
| SCHEMBL25269473 | 0.69 | SCD (0.37) | PDE4DPDE1APDE1BPDE1CGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534665-A | Diacylglycerol kinase inhibitors | 山东轩竹医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |