Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479964 | 0.88 | SMN1; SMN2 (0.47) | ALDH1A1POLBMAPK1SMN1; SMN2LMNA | |
| SCHEMBL31480016 | 0.87 | ALDH1A1 (0.49) | ALDH1A1GAANR1H2NR1H3POLB | |
| SCHEMBL7445245 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KMT2AALOX15HSD17B10GAA | |
| SCHEMBL7297001 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2AHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL8922653 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL7445085 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KMT2AGAALMNAOPRD1 | |
| SCHEMBL12821356 | 0.72 | ALDH1A1 (0.71) | ALDH1A1KMT2AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL6800724 | 0.71 | SMN1; SMN2 (0.46) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22406302 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KMT2APOLBMAPK1SMN1; SMN2 | |
| SCHEMBL21383627 | 0.71 | ALDH1A1 (0.68) | ALDH1A1KMT2AALOX15HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051434-A1 | MONOVALENT INTERLEUKIN 12 (IL-12) HETERODIMERIC FC PROTEINS | MERCK SHARP & DOHME LLC (US) | 2025-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051434-A1 | MONOVALENT INTERLEUKIN 12 (IL-12) HETERODIMERIC FC PROTEINS | IL2RA, IL2, FCGR2A | ALDH1A1 4345/4885KMT2A 2295/4885ALOX15 1808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.