SCHEMBL31480080

SCHEMBL31480080

CCNc1cc(C(=O)OC)ccc1C1CC2(CCN1)COC2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4D Q08499 1/20 0.36
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 6/20 0.34
MAPT P10636 3/20 0.34
HPGD P15428 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
MAPKAPK2 P49137 1/20 0.33
LMNA P02545 1/20 0.33
CREBBP Q92793 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31480286 0.89 ALDH1A1 (0.36) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL31480262 0.81 ALDH1A1 (0.38) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL31480092 0.80 PTGER4 (0.32) KDM4EALDH1A1MAPTNPSR1ALOX15
SCHEMBL25320269 0.79 NPC1 (0.47) KMT2AMEN1ATML3MBTL1KDM4E
SCHEMBL31140824 0.79 NPC1 (0.47) KMT2AMEN1ATML3MBTL1KDM4E
SCHEMBL31480499 0.78 CNR2 (0.36) KDM4EALDH1A1ALOX15CREBBP
SCHEMBL31480175 0.78 PTGER4 (0.39) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL31480330 0.78 PTGER4 (0.37) KMT2AKDM4EALDH1A1MAPTHPGD
SCHEMBL31480383 0.76 KCNH2 (0.31) KDM4EALDH1A1MAPTNPSR1
SCHEMBL31480467 0.74 ALDH1A1 (0.35) KMT2AMEN1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054361-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2025-03-13 WO disclosed