Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480286 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTNPSR1CHRNB2 | |
| SCHEMBL31480080 | 0.81 | KMT2A (0.36) | ALDH1A1KDM4EMAPTNPSR1CHRNB2 | |
| SCHEMBL31480229 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTNPSR1CHRNB2 | |
| SCHEMBL31480467 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4EMAPTNPSR1CHRNB2 | |
| SCHEMBL31480447 | 0.79 | MAPT (0.33) | ALDH1A1KDM4EMAPTNPSR1CHRNB2 | |
| SCHEMBL16400464 | 0.79 | NPC1 (0.45) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL31480315 | 0.78 | NISCH (0.37) | ALDH1A1KDM4EMAPTNPSR1CHRNB2 | |
| SCHEMBL31480330 | 0.77 | PTGER4 (0.37) | ALDH1A1KDM4EMAPTNPSR1CHRNB2 | |
| SCHEMBL31480332 | 0.76 | CRBN (0.32) | MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL31480509 | 0.76 | CRBN (0.32) | MAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |