Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056028 | 0.89 | NOTUM (0.51) | KDM4ENOTUMALDH1A1HPGDATM | |
| SCHEMBL31359219 | 0.89 | NOTUM (0.51) | KDM4ENOTUMALDH1A1HPGDATM | |
| SCHEMBL16318447 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1HPGDATMGLA | |
| SCHEMBL10318265 | 0.84 | ALDH1A1 (0.50) | KDM4ENOTUMALDH1A1HPGDATM | |
| SCHEMBL2934675 | 0.84 | CA12 (0.54) | KDM4EALDH1A1HPGDATMGLA | |
| SCHEMBL29281561 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDATMGLA | |
| SCHEMBL3601292 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1HPGDATMGLA | |
| SCHEMBL30816858 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDATMGLA | |
| SCHEMBL4490699 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDATMGLA | |
| SCHEMBL11303925 | 0.82 | KDM4E (0.46) | KDM4ENOTUMALDH1A1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |