SCHEMBL31480225

SCHEMBL31480225

O=C(OC1CC2(CCN1)CC(F)(F)C2)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.43
CHRNA7 P36544 2/20 0.38
TSHR P16473 2/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CHRM2 P08172 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
CHRM4 P08173 1/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34
HTR3A P46098 1/20 0.34
HTR3D Q70Z44 1/20 0.34
HTR3C Q8WXA8 1/20 0.34
LMNA P02545 2/20 0.33
F2 P00734 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31480462 0.80 KDM4E (0.43) LMNATDP1
SCHEMBL6825919 0.79 GAA (0.54) GAACHRNA7TSHRAPOBEC3AAPOBEC3G
SCHEMBL6830828 0.75 GAA (0.50) GAACHRNA7TSHRAPOBEC3AAPOBEC3G
SCHEMBL27499699 0.72 CHRNA7 (0.56) GAACHRNA7TSHRAPOBEC3AAPOBEC3G
SCHEMBL27301151 0.71 CHRNA7 (0.51) GAACHRNA7APOBEC3AAPOBEC3GKMT2A
SCHEMBL26105561 0.70 CHRNA7 (0.50) GAACHRNA7TSHRKMT2AMEN1
SCHEMBL25318693 0.70 NPC1 (0.40) GAATSHRKMT2AMEN1TDP1
SCHEMBL31140806 0.70 NPC1 (0.40) GAATSHRKMT2AMEN1TDP1
SCHEMBL11056537 0.69 CHRNA7 (0.49) GAACHRNA7TSHRKMT2AMEN1
SCHEMBL25317458 0.69 MAOB (0.35) TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054361-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2025-03-13 WO disclosed