Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
| ▸ | HTR3B | O95264 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825919 | 0.85 | GAA (0.54) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL31480225 | 0.75 | GAA (0.43) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL27499699 | 0.73 | CHRNA7 (0.56) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL27301151 | 0.72 | CHRNA7 (0.51) | GAAKMT2ACHRNA7MEN1LMNA | |
| SCHEMBL26105561 | 0.71 | CHRNA7 (0.50) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL11056537 | 0.70 | CHRNA7 (0.49) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL27134058 | 0.67 | GAA (0.55) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL4702654 | 0.67 | GAA (0.55) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL97715 | 0.67 | GAA (1.00) | GAATSHRKMT2ACHRNA7MEN1 | |
| SCHEMBL8183692 | 0.66 | GAA (0.58) | GAATSHRKMT2ACHRNA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |