Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480389 | 0.88 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL10874779 | 0.85 | NPC1 (0.68) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL7595080 | 0.79 | MGLL (0.49) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2276099 | 0.79 | KDM4E (0.66) | RAB9ACYP1A2CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL1095126 | 0.79 | CASP3 (0.58) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL5056843 | 0.78 | CYP2C19 (0.60) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL31480254 | 0.78 | NPC1 (0.46) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL27567788 | 0.78 | CYP1A2 (0.63) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL10192674 | 0.77 | NPC1 (0.64) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL1490611 | 0.77 | NPC1 (0.57) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |