Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765248 | 1.00 | DEPTOR (0.40) | DEPTORALDH1A1POLBGAANPSR1 | |
| SCHEMBL29711832 | 0.84 | DEPTOR (0.43) | DEPTORALDH1A1GAARAPGEF4SMN1; SMN2 | |
| SCHEMBL28765184 | 0.84 | DEPTOR (0.43) | DEPTORALDH1A1GAARAPGEF4SMN1; SMN2 | |
| SCHEMBL28765241 | 0.84 | DEPTOR (0.43) | DEPTORALDH1A1GAARAPGEF4SMN1; SMN2 | |
| SCHEMBL31482885 | 0.80 | DEPTOR (0.40) | DEPTORALDH1A1POLBGAARAPGEF4 | |
| SCHEMBL22968434 | 0.80 | DEPTOR (0.40) | DEPTORALDH1A1POLBGAARAPGEF4 | |
| SCHEMBL31482887 | 0.78 | TSHR (0.43) | DEPTORGAASMN1; SMN2MAPTTP53 | |
| SCHEMBL28765116 | 0.78 | TSHR (0.43) | DEPTORGAASMN1; SMN2MAPTTP53 | |
| SCHEMBL31482884 | 0.77 | DEPTOR (0.40) | DEPTORALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL28765252 | 0.77 | DEPTOR (0.40) | DEPTORALDH1A1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555603-B | Improved synthetic methods for preparing (2H-1, 2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2025-03-14 | — | — | CN | disclosed |