Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | ITK | Q08881 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23675231 | 1.00 | ACACB (0.48) | ACACBACACALRRK2VNN1MEN1 | |
| SCHEMBL23680895 | 0.79 | HTR1A (0.48) | ACACBACACALRRK2HPGDHSD11B1 | |
| SCHEMBL23680834 | 0.77 | CNR2 (0.41) | HPGDBTKPAK1 | |
| SCHEMBL23675147 | 0.76 | PLK4 (0.56) | LRRK2VNN1HPGDJAK1 | |
| SCHEMBL24329725 | 0.76 | LRRK2 (0.43) | LRRK2HPGDHSD11B1 | |
| SCHEMBL29564788 | 0.75 | AXL (0.45) | ACACBACACABTKITK | |
| SCHEMBL2671287 | 0.75 | AXL (0.45) | ACACBACACABTKITK | |
| SCHEMBL17786923 | 0.74 | ITK (0.45) | ACACBACACALRRK2NTRK1BTK | |
| SCHEMBL24758082 | 0.73 | NTRK1 (0.48) | ACACBACACALRRK2VNN1KMT2A | |
| SCHEMBL23680844 | 0.72 | MGLL (0.57) | JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335043-B | PGDH inhibitors and methods of making and using the same | 迈欧伏特治疗公司 | 2025-03-28 | — | — | CN | disclosed |