Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.61 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483021 | 0.89 | PIK3CA (0.49) | PIK3CAPIK3CGPIK3CDMTORAKT1 | |
| SCHEMBL22371014 | 0.84 | PIK3CA (0.52) | PIK3CARIPK1 | |
| SCHEMBL3232733 | 0.82 | BRD4 (0.53) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL30468343 | 0.82 | PIK3CA (0.52) | PIK3CARIPK1 | |
| SCHEMBL22371046 | 0.82 | PIK3CA (0.52) | PIK3CARIPK1 | |
| Lithium Ion SCHEMBL29849231 | 0.81 | PIK3CA (0.49) | PIK3CAMTORAKT1RIPK1 | |
| SCHEMBL13188559 | 0.79 | FYN (0.56) | PIK3CA | |
| SCHEMBL2920182 | 0.79 | PIK3CA (0.80) | PIK3CAPIK3CGPIK3CDRIPK1 | |
| SCHEMBL798566 | 0.78 | PIK3CG (0.50) | PIK3CAPIK3CGPIK3CDMTORAKT1 | |
| SCHEMBL31483093 | 0.76 | PIK3CG (1.00) | PIK3CAPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |