SCHEMBL31483071

SCHEMBL31483071

NC(=O)NCCNc1cccnc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.55
CDK2 P24941 1/20 0.51
FLT4 P35916 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
PKM P14618 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 2/20 0.45
HIF1A Q16665 1/20 0.45
CYP11B2 P19099 2/20 0.44
CYP11B1 P15538 1/20 0.44
ALOX15 P16050 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NAMPT P43490 1/20 0.44
F7 P08709 1/20 0.43
F3 P13726 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841015 0.79 EPHX1 (0.51) L3MBTL1HSD17B10ALDH1A1TP53
SCHEMBL4572898 0.78 RAB9A (0.50) RECQLCDK2FLT4L3MBTL1RAB9A
SCHEMBL3208241 0.77 NPC1 (0.53) CDK2FLT4L3MBTL1RAB9ANPC1
SCHEMBL21087536 0.76 CYP2A6 (0.50) CDK2FLT4RAB9AMEN1KMT2A
SCHEMBL4572901 0.75 RAB9A (0.50) CDK2FLT4RAB9ANPC1PKM
SCHEMBL4383419 0.75 RAB9A (0.50) RECQLCDK2FLT4L3MBTL1RAB9A
SCHEMBL29655934 0.75 RAB9A (0.65) CDK2FLT4RAB9ANPC1PKM
SCHEMBL162008 0.75 RAB9A (0.65) CDK2FLT4RAB9ANPC1PKM
SCHEMBL2755854 0.75 RECQL (0.71) RECQLFLT4RAB9ANPC1MEN1
SCHEMBL22851453 0.74 RAB9A (0.53) CDK2FLT4L3MBTL1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841829-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2025-04-18 CN disclosed