Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652465 | 0.87 | TBXAS1 (0.57) | CDK2FLT4TBXAS1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL3571748 | 0.82 | NPC1 (0.56) | NPC1PKMRAB9ACDK2FLT4 | |
| SCHEMBL30402824 | 0.82 | NPC1 (0.56) | NPC1PKMRAB9ACDK2FLT4 | |
| SCHEMBL2450853 | 0.82 | NPC1 (0.56) | NPC1PKMRAB9ACDK2FLT4 | |
| SCHEMBL13588769 | 0.81 | RAB9A (0.46) | NPC1PKMRAB9ACDK2FLT4 | |
| Bromide SCHEMBL10884497 | 0.81 | NPC1 (0.54) | NPC1PKMRAB9ACDK2FLT4 | |
| Phenamino Methyl Acetic Acid SCHEMBL433918 | 0.79 | POLB (0.59) | SMN1; SMN2L3MBTL1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL7364359 | 0.79 | TOP2A (0.51) | NPC1PKMRAB9AALDH1A1TBXAS1 | |
| SCHEMBL4383419 | 0.78 | RAB9A (0.50) | NPC1PKMRAB9ACDK2FLT4 | |
| SCHEMBL3197308 | 0.78 | BCHE (0.59) | SMN1; SMN2L3MBTL1ALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966454-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-05-07 | — | — | EP | claimed |
| US-8937090-B2 | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO COMPANY, LTD. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | SHISEIDO COMPANY, LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-1941861-A1 | WRINKLE-IMPROVING AGENT | Shiseido Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1880711-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| US-20050009151-A1 | Methods for the stereospecific and enantiomeric enrichment of beta-amino acids | PHARMACIA CORPORATION | 2005-01-13 | — | — | US | disclosed |
| EP-1321454-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | Kaneka Corporation (JP) | 2003-06-25 | — | — | EP | disclosed |
| US-6515179-B2 | Reacting nitrobenzenesulfonyl group containing compound contacting with alkali metal alkoxide | KANEKA CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20030009056-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | KANEKA CORPORATION (JP) | 2003-01-09 | — | — | US | disclosed |
| CN-1355811-A | Integrain receptor antagaonists | BASF AG (DE) | 2002-06-26 | — | — | CN | disclosed |
| US-5889023-A | 3(R)-(2-(PIPERIDIN-4-YL)ETHYL)-2-PIPERIDON-1-YLACETYL-3(S)-3-( PYRIDYL)-BETA-ALANINE OR SALT USED AS AN ANTICOAGULANT | MERCK & CO., INC. (US) | 1999-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | NPC1 3469/4885PKM 2042/4885RAB9A 3240/4885 |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | CUTA, AAAS, NUP160 | NPC1 1049/4885PKM 263/4885RAB9A 4613/4885 |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | NPC1 3438/4885PKM 2006/4885RAB9A 3250/4885 |
| US-20030009056-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | NAAA, TST, AADAC | NPC1 4479/4885PKM 2396/4885RAB9A 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.