Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 8/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796763 | 0.72 | TNKS2 (0.56) | KMT2AELANETNKS2PDE3BPDE3A | |
| SCHEMBL1685046 | 0.71 | TNKS2 (0.70) | KMT2ATNKS2PARP1QTRT1MEN1 | |
| SCHEMBL4408698 | 0.71 | ELANE (0.70) | KMT2AELANEMEN1 | |
| SCHEMBL29967198 | 0.71 | TNKS2 (0.70) | KMT2ATNKS2PARP1QTRT1MEN1 | |
| SCHEMBL5477868 | 0.71 | MAPT (0.53) | TNKS2PDE3BPDE3APARP1QTRT1 | |
| SCHEMBL16914813 | 0.68 | KDM4E (0.53) | KMT2ATNKS2PARP1MEN1TNKS | |
| SCHEMBL5126044 | 0.67 | KMT2A (0.54) | KMT2APARP1MEN1KDM4EALDH1A1 | |
| SCHEMBL7526687 | 0.66 | PDE10A (0.69) | KMT2ATNKS2PARP1MEN1KDM4E | |
| SCHEMBL23668740 | 0.65 | ELANE (0.71) | KMT2AELANEMEN1KDM4EALDH1A1 | |
| SCHEMBL26314517 | 0.65 | PARP1 (0.47) | KMT2AELANETNKS2PARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699176-B | Quinazolinones as PARP14 inhibitors | 里邦医疗公司 | 2025-02-14 | — | — | CN | disclosed |