Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 17/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | C1R | P00736 | 2/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692733 | 0.85 | ELANE (0.81) | ELANEMEN1KMT2AC1RPDE10A | |
| SCHEMBL6136297 | 0.85 | ELANE (0.83) | ELANEMEN1KMT2AC1RPDE10A | |
| SCHEMBL29405904 | 0.85 | ELANE (0.81) | ELANEMEN1KMT2AC1RPDE10A | |
| SCHEMBL1038894 | 0.83 | ELANE (0.68) | ELANEMEN1KMT2AC1RPDE10A | |
| SCHEMBL2812822 | 0.82 | ELANE (0.76) | ELANEMEN1KMT2AC1R | |
| SCHEMBL29444886 | 0.82 | ELANE (0.76) | ELANEMEN1KMT2AC1RPDE10A | |
| SCHEMBL10550516 | 0.82 | ELANE (1.00) | ELANEMEN1KMT2AC1R | |
| SCHEMBL692829 | 0.82 | ELANE (0.76) | ELANEMEN1KMT2AC1RPDE10A | |
| SCHEMBL6262346 | 0.81 | ELANE (1.00) | ELANEMEN1KMT2AC1R | |
| SCHEMBL2572932 | 0.81 | ELANE (0.73) | ELANEMEN1KMT2AC1RPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12319661-B2 | Polycyclic compound | EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) | 2025-06-03 | — | — | US | disclosed |
| CN-115745970-B | Polycyclic compound, preparation method and membrane | 江苏裕事达新材料科技有限责任公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-111285853-B | Polycyclic compound | 江苏裕事达新材料科技有限责任公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-115745970-A | Polycyclic compound, preparation method and film | 江苏裕事达新材料科技有限责任公司 | 2023-03-07 | — | — | CN | disclosed |
| US-20220017474-A1 | Novel Polycyclic Compound | EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) | 2022-01-20 | — | — | US | disclosed |
| EP-3896067-A1 | NOVEL POLYCYCLIC COMPOUND | Eutec New Materials Technology (Suzhou) Co., Ltd (CN) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020118933-A1 | NOVEL POLYCYCLIC COMPOUND | 优缔新材料科技(苏州)有限公司 | 2020-06-18 | — | — | WO | disclosed |
| CN-111285853-A | Novel polycyclic compound | 优缔新材料科技(苏州)有限公司 | 2020-06-16 | — | — | CN | disclosed |
| US-8518959-B2 | Quinoxaline derivatives as antitumor agents | PROLEXYS PHARMACEUTICALS, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-8518959-B2 | Quinoxaline derivatives as antitumor agents | PROLEXYS PHARMACEUTICALS, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-7615554-B2 | Erastin and erastin binding proteins, and uses thereof | PROLEXYS PHARMACEUTICALS, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615554-B2 | Erastin and erastin binding proteins, and uses thereof | PROLEXYS PHARMACEUTICALS, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-20090214465-A1 | Quinoxaline Derivatives as Antitumor Agents | PROLEXYS PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090214465-A1 | Quinoxaline Derivatives as Antitumor Agents | PROLEXYS PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090214465-A1 | Quinoxaline Derivatives as Antitumor Agents | PROLEXYS PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| WO-2008013840-A2 | ERASTIN ANALOGS AND USES THEREOF | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-01-31 | — | — | WO | disclosed |
| US-20070161644-A1 | Erastin analogs and uses thereof | STOCKWELL BRENT R | 2007-07-12 | — | — | US | disclosed |
| US-20070161644-A1 | Erastin analogs and uses thereof | STOCKWELL BRENT R | 2007-07-12 | — | — | US | disclosed |
| US-20070161644-A1 | Erastin analogs and uses thereof | STOCKWELL BRENT R | 2007-07-12 | — | — | US | disclosed |
| US-20060211683-A1 | Erastin and erastin binding proteins, and uses thereof | PROLEXYS PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161644-A1 | Erastin analogs and uses thereof | ERAP2, ERAP1, ERAL1 | ELANE 229/4885MEN1 397/4885KMT2A 3738/4885 |
| US-20060211683-A1 | Erastin and erastin binding proteins, and uses thereof | VDAC3, ERAL1, VDAC2 | ELANE 2327/4885MEN1 2995/4885KMT2A 4378/4885 |
| US-12319661-B2 | Polycyclic compound | CUTA, CDH1, DSG1 | ELANE 3050/4885MEN1 485/4885KMT2A 3118/4885 |
| US-20220017474-A1 | Novel Polycyclic Compound | CUTA, DSG1, UACA | ELANE 3327/4885MEN1 639/4885KMT2A 2775/4885 |
| US-20090214465-A1 | Quinoxaline Derivatives as Antitumor Agents | VDAC3, VDAC2, VDAC1 | ELANE 3398/4885MEN1 2178/4885KMT2A 3575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.