SCHEMBL31484019

SCHEMBL31484019

CC(C)(C)OC(=O)NCCn1ccc2cc(Br)ncc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 6/20 0.43
MTNR1B P49286 6/20 0.43
MAPK1 P28482 3/20 0.40
CKS1B P61024 1/20 0.40
SKP1 P63208 1/20 0.40
SKP2 Q13309 1/20 0.40
BCHE P06276 1/20 0.39
STK17B O94768 1/20 0.39
STK17A Q9UEE5 1/20 0.39
SCN9A Q15858 1/20 0.39
SUV39H2 Q9H5I1 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24110580 0.88 MTNR1A (0.47) MTNR1AMTNR1BMAPK1SMN1; SMN2
SCHEMBL7672969 0.81 MTNR1A (0.51) MTNR1AMTNR1BMAPK1LMNAMAPT
SCHEMBL18935522 0.79 MTNR1A (0.51) MTNR1AMTNR1BMAPK1LMNASMN1; SMN2
SCHEMBL31484134 0.79 HTR2C (0.36)
SCHEMBL12985213 0.79 MTNR1A (0.45) MTNR1AMTNR1BCKS1BSKP1SKP2
SCHEMBL31130021 0.79 MTNR1A (0.44) MTNR1AMTNR1BMAPK1LMNASMN1; SMN2
SCHEMBL3417837 0.78 MTNR1A (0.50) MTNR1AMTNR1BMAPK1LMNASMN1; SMN2
SCHEMBL21268786 0.78 MTNR1A (0.54) MTNR1AMTNR1BMAPK1CKS1BSKP1
SCHEMBL23116611 0.77 MAPK1 (0.67) MTNR1AMTNR1BMAPK1LMNAMAPT
Trifluoroacetic Acid SCHEMBL30207678 0.77 MTNR1A (0.42) MTNR1AMTNR1BMAPK1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611925-B HPK1 inhibitors and uses thereof 轩竹生物科技股份有限公司 2025-04-08 CN disclosed