Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298737 | 0.87 | ABCG2 (0.52) | ABCG2SLC2A1CDC7SYKABCB1 | |
| SCHEMBL31484155 | 0.87 | KMT2A (0.49) | ABCG2ABCB1ABCC1NPC1SMN1; SMN2 | |
| SCHEMBL31484106 | 0.85 | ABCG2 (0.49) | ABCG2ABCB1ABCC1RAB9A | |
| SCHEMBL31484092 | 0.84 | ABCB1 (0.44) | ABCG2ABCB1ABCC1AGPAT2KDR | |
| SCHEMBL31484220 | 0.84 | NFKB1 (0.56) | ABCG2SLC2A1NPC1RAB9A | |
| SCHEMBL31484093 | 0.81 | MAPT (0.54) | ABCG2ABCB1ABCC1NPC1RAB9A | |
| SCHEMBL31484062 | 0.81 | SLC2A1 (0.54) | ABCG2SLC2A1CDC7SYKABCB1 | |
| SCHEMBL31484168 | 0.80 | ALDH1A1 (0.44) | ABCG2ABCB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8973372 | 0.79 | NFKB1 (0.59) | ABCG2SLC2A1CDC7SYK | |
| SCHEMBL31484161 | 0.79 | NPC1 (0.45) | ABCG2ABCB1NPC1RAB9AAGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431324-A | 1- (4/5-Cyano-6-substituted pyrimidine-2-yl) -1H-pyrazole-4-formic acid compound, and preparation method and application thereof | 沈阳药科大学 | 2025-02-14 | — | — | CN | disclosed |