⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501596 | 0.78 | MEN1 (0.34) | — | |
| SCHEMBL17547305 | 0.76 | — | — | |
| SCHEMBL6189041 | 0.76 | — | — | |
| SCHEMBL9479129 | 0.76 | — | — | |
| SCHEMBL9505628 | 0.72 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL9827215 | 0.72 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL8553415 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL31241304 | 0.70 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL11235845 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL9827332 | 0.69 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2138270-A | — | — | None | — | — | JP | disclosed |
| US-20250339541-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250213699-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2025-07-03 | — | — | US | disclosed |
| US-12290568-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2025-05-06 | — | — | US | disclosed |
| WO-2025085848-A1 | ANTIBACTERIAL COMPOUNDS | ARREPATH, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| US-12280116-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| CN-119192200-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2024-12-27 | — | — | CN | disclosed |
| US-20240424108-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-12-26 | — | — | US | disclosed |
| US-12162888-B2 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-12128106-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2024-10-29 | — | — | US | disclosed |
| EP-0509341-A1 | Cyanothiazole derivatives | BAYER AG (DE) | 1992-10-21 | — | — | EP | disclosed |
| US-5090991-A | HERBICIDAL N-ISOPROPYLHETEROARYLOXYACETANILIDES | BAYER AKATIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4968342-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| JP-H02138270-A | SUBSTITUTED 2-CHLORO-5-CYANOTHIAZOLE AND PREPARATION THEREOF | BAYER AG | 1990-05-28 | — | — | JP | disclosed |
| EP-0115811-B1 | 2,4-DICHLOR-5-THIAZOLECARBOXALDEHYD AND A PROCESS FOR ITS PREPARATION | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |
| EP-0348737-A1 | Heteroaryloxy-acetic acid N-isopropyl anilides | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |
| EP-0316731-A2 | Azo dyes from 2-hydrazinothiazole, their use in dyeing and printing fibre materials, and in sublimation transfer printing | BAYER AG (DE) | 1989-05-24 | — | — | EP | disclosed |
| US-4555577-A | 2,4-Dichloro-5-thiazolecarboxaldehyde and a process for its preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |
| EP-0115811-A2 | 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation | BAYER AG (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0115811-A2 | 2,4-Dichlor-5-thiazolecarboxaldehyd and a process for its preparation | BAYER AG (DE) | 1984-08-15 | — | — | EP | disclosed |