SCHEMBL9501596

SCHEMBL9501596

N#Cc1nc(Cl)sc1C#N

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8808626 0.78
SCHEMBL3148442 0.78
SCHEMBL6189041 0.74
SCHEMBL17088286 0.71 KDM4E (0.34) SMN1; SMN2KDM4EGAA
SCHEMBL5537146 0.71 KDM4E (0.34) SMN1; SMN2KDM4E
SCHEMBL10968419 0.71
SCHEMBL11224659 0.69 GAA (0.31) GAA
SCHEMBL9503430 0.67 KDM4E (0.36) MEN1KMT2ASMN1; SMN2KDM4EGAA
SCHEMBL18387206 0.67 MAPK1 (0.36) KDM4EGAA
SCHEMBL21283213 0.64 CDC7 (0.41) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0316731-B1 AZO DYES FROM 2-HYDRAZINOTHIAZOLE, THEIR USE IN DYEING AND PRINTING FIBRE MATERIALS, AND IN SUBLIMATION TRANSFER PRINTING BAYER AG (DE) 1993-05-19 EP disclosed
EP-0316731-A2 Azo dyes from 2-hydrazinothiazole, their use in dyeing and printing fibre materials, and in sublimation transfer printing BAYER AG (DE) 1989-05-24 EP disclosed