Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 13/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22933155 | 0.78 | CD38 (0.53) | CD38 | |
| SCHEMBL22933151 | 0.71 | CD38 (0.77) | CD38 | |
| SCHEMBL22936235 | 0.70 | CD38 (0.77) | CD38 | |
| SCHEMBL29495195 | 0.70 | CD38 (0.38) | CHEK1CHEK2CD38MYC | |
| SCHEMBL1786530 | 0.70 | CD38 (0.50) | CHEK1CHEK2CD38LRRK2CHUK | |
| SCHEMBL4061758 | 0.70 | PARP1 (0.40) | CHEK1LRRK2IKBKBCHUKPI4K2A | |
| SCHEMBL23123126 | 0.69 | QPCT (0.41) | CD38 | |
| SCHEMBL30567526 | 0.68 | SCN9A (0.41) | — | |
| SCHEMBL619206 | 0.67 | IKBKB (0.66) | CD38IKBKBCHUK | |
| SCHEMBL619205 | 0.67 | IKBKB (0.56) | CD38IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |