Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FSHR | P23945 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.37 |
| ▸ | WHR1 | P49842 | 2/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31485338 | 0.83 | GSK3B (0.41) | GSK3BDYRK1ATSHRFSHRSCN10A | |
| SCHEMBL31485400 | 0.82 | SCN10A (0.44) | GSK3BDYRK1ATSHRFSHRSCN10A | |
| SCHEMBL31485279 | 0.78 | KIF18A (0.49) | KIF18A | |
| SCHEMBL26650662 | 0.76 | SCN10A (0.35) | GSK3BDYRK1ASCN10AWHR1KIF18A | |
| SCHEMBL26650968 | 0.74 | NOS3 (0.36) | SCN10AWHR1 | |
| SCHEMBL26650429 | 0.74 | NOS3 (0.41) | SCN10AWHR1 | |
| SCHEMBL26650701 | 0.73 | SCN10A (0.41) | SCN10AWHR1 | |
| SCHEMBL26650666 | 0.72 | SCN10A (0.36) | GSK3BTSHRFSHRSCN10AWHR1 | |
| SCHEMBL29988330 | 0.72 | TSHR (0.43) | GSK3BDYRK1ATSHRFSHRSCN10A | |
| SCHEMBL26507319 | 0.72 | TSHR (0.43) | GSK3BDYRK1ATSHRFSHRSCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |