Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31148426 | 1.00 | HTT (0.43) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| SCHEMBL31485466 | 0.96 | HTT (0.46) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| SCHEMBL31485476 | 0.96 | HTT (0.46) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| Hydrochloric Acid SCHEMBL25421188 | 0.95 | HTT (0.45) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| Hydrochloric Acid SCHEMBL30421555 | 0.95 | HTT (0.45) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| Hydrochloric Acid SCHEMBL25421178 | 0.95 | HTT (0.45) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| Trifluoroacetic Acid SCHEMBL31148452 | 0.93 | HTT (0.51) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| SCHEMBL31485471 | 0.88 | HTT (0.55) | HTTMAPTCTNNB1TCF7L2PTPN11 | |
| Trifluoroacetic Acid SCHEMBL30422964 | 0.88 | MAPT (0.43) | MAPTPTPN11POLB | |
| Trifluoroacetic Acid SCHEMBL30422633 | 0.88 | MAPT (0.37) | HTTMAPTPTPN11POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122192-A1 | 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122192-A1 | 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND METHODS OF USING THE SAME | RTCB, NSUN2, PRPF19 | HTT 3559/4885MAPT 4668/4885CTNNB1 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.