Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31485514 | 0.88 | CSNK2A2 (0.44) | LATS1ADORA3KDM4EALDH1A1TDO2 | |
| SCHEMBL31485594 | 0.87 | LATS1 (0.56) | LATS1MAPTADORA3KDM4EADORA1 | |
| SCHEMBL31356303 | 0.86 | LATS1 (0.56) | LATS1MAPTMAPK1HTTEGFR | |
| SCHEMBL31485510 | 0.84 | LATS1 (0.39) | LATS1MAPTMAPK1ADORA3KDM4E | |
| SCHEMBL31485515 | 0.79 | CSNK2A1 (0.49) | KDM4EALDH1A1EGFRCHEK1 | |
| SCHEMBL31485528 | 0.79 | CSNK2A1 (0.53) | HTTEGFRRAB9AMEN1KMT2A | |
| SCHEMBL31485519 | 0.79 | IDO1 (0.45) | LATS1TDO2EGFR | |
| SCHEMBL31485477 | 0.79 | ABCG2 (0.47) | LATS1EGFRCHUK | |
| SCHEMBL27199806 | 0.78 | LATS1 (0.47) | LATS1MAPTMAPK1HTTADORA3 | |
| SCHEMBL31356296 | 0.78 | LATS1 (0.49) | LATS1MAPTMAPK1HTTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-04-08 | — | — | US | claimed |
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | CKS2, CSNK1G1, CSNK2A3 | LATS1 1067/4885MAPT 976/4885MAPK1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.