Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.56 |
| ▸ | CLK1 | P49759 | 6/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.44 |
| ▸ | CLK2 | P49760 | 4/20 | 0.44 |
| ▸ | CLK3 | P49761 | 4/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.44 |
| ▸ | CHUK | O15111 | 2/20 | 0.44 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31485537 | 0.87 | LATS1 (0.53) | LATS1CHUKMEN1KMT2AADORA3 | |
| SCHEMBL31485528 | 0.87 | CSNK2A1 (0.53) | CLK1CDK5DYRK1ACDK5R1CLK2 | |
| SCHEMBL31485514 | 0.85 | CSNK2A2 (0.44) | LATS1DYRK1ACHUKADORA3NPY5R | |
| SCHEMBL27199804 | 0.80 | LATS1 (0.50) | LATS1CLK1CDK5DYRK1ACDK5R1 | |
| SCHEMBL27171319 | 0.80 | LATS1 (0.50) | LATS1CLK1CDK5DYRK1ACDK5R1 | |
| SCHEMBL31356293 | 0.79 | LATS1 (0.52) | LATS1CHUKPTK6MEN1KMT2A | |
| SCHEMBL31485510 | 0.79 | LATS1 (0.39) | LATS1CDK5DYRK1ACDK5R1CHUK | |
| SCHEMBL31356303 | 0.79 | LATS1 (0.56) | LATS1MEN1KMT2AABCG2MAPT | |
| SCHEMBL27074286 | 0.77 | CSNK2A1 (0.57) | CLK1CDK5DYRK1ACLK2CLK3 | |
| SCHEMBL31485515 | 0.76 | CSNK2A1 (0.49) | CLK1CDK5DYRK1ACLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-04-08 | — | — | US | claimed |
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | CKS2, CSNK1G1, CSNK2A3 | LATS1 1067/4885CLK1 243/4885CDK5 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.