Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 19/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31486600 | 0.95 | F2 (0.43) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6994894 | 0.91 | F2 (0.54) | F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7992112 | 0.90 | F2 (0.53) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL31486396 | 0.89 | F2 (0.40) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6997351 | 0.88 | F2 (0.49) | F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7978029 | 0.87 | F2 (0.49) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6991514 | 0.85 | F2 (0.64) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6994201 | 0.85 | F2 (0.64) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6997888 | 0.85 | F2 (0.64) | F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7996054 | 0.85 | F2 (0.64) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122225-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-17 | — | — | US | disclosed |
| WO-2025076476-A2 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122225-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, SPINT2, SERPINB1 | F2 117/4885PRSS1 20/4885PRSS2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.