Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 5/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31486384 | 0.84 | MAPK14 (0.35) | PREPACEP2RX7 | |
| SCHEMBL31486546 | 0.83 | RPS6KB1 (0.39) | PREPJAK2JAK3 | |
| Trifluoroacetic Acid SCHEMBL31486245 | 0.79 | PDPK1 (0.33) | — | |
| SCHEMBL31486305 | 0.78 | MAPK14 (0.37) | WDR5PREPJAK3 | |
| SCHEMBL6073947 | 0.78 | ACE (0.35) | PREPACE | |
| SCHEMBL31486475 | 0.76 | PREP (0.43) | PREP | |
| SCHEMBL31486336 | 0.73 | AOC3 (0.42) | PREPFFAR1 | |
| SCHEMBL31486332 | 0.72 | BCHE (0.37) | PREP | |
| SCHEMBL31486261 | 0.72 | MAPK14 (0.37) | PREPFFAR1 | |
| SCHEMBL31486369 | 0.72 | PTK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122225-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-17 | — | — | US | disclosed |
| WO-2025076476-A2 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122225-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, SPINT2, SERPINB1 | WDR5 3606/4885PREP 140/4885FFAR1 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.