Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19699851 | 1.00 | EGFR (0.55) | EGFRIMPDH2ASH1LCDK5CDK5R1 | |
| SCHEMBL29212194 | 0.77 | BRD4 (0.48) | IMPDH2CDK5CDK5R1SMN1; SMN2KDM4E | |
| SCHEMBL19089318 | 0.77 | EGFR (0.55) | EGFRIMPDH2CDK5CDK5R1CYP1A2 | |
| SCHEMBL29419125 | 0.73 | MKNK1 (0.50) | EGFRIMPDH2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL5096322 | 0.73 | MKNK1 (0.50) | EGFRIMPDH2CDK5CDK5R1SMN1; SMN2 | |
| SCHEMBL1310255 | 0.73 | IMPDH2 (0.64) | IMPDH2ASH1LCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30320839 | 0.73 | BRD4 (0.67) | IMPDH2CDK5CDK5R1CYP1A2CYP3A4 | |
| SCHEMBL3974232 | 0.71 | POLB (0.62) | SMN1; SMN2NPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL16416083 | 0.71 | CDK5 (0.47) | EGFRIMPDH2CDK5CDK5R1CYP1A2 | |
| SCHEMBL20549072 | 0.71 | KDM4E (0.45) | IMPDH2CDK5CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562809-A | Inhibitors of tau protein | 德国神经退行性疾病研究中心 | 2025-03-04 | — | — | CN | disclosed |