Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 3/20 | 0.58 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.58 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488408 | 0.86 | IMPDH2 (0.58) | IMPDH2BRD4ALDH1A1KDM4ENPC1 | |
| SCHEMBL9300549 | 0.85 | IMPDH2 (0.57) | IMPDH2BRD4ALDH1A1KDM4ENPC1 | |
| SCHEMBL3131200 | 0.85 | IMPDH2 (0.57) | IMPDH2BRD4ALDH1A1KDM4ENPC1 | |
| SCHEMBL28241926 | 0.85 | IMPDH2 (0.57) | IMPDH2BRD4ALDH1A1KDM4ENPC1 | |
| SCHEMBL28271167 | 0.81 | IMPDH2 (0.53) | IMPDH2ALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL3149953 | 0.81 | IMPDH2 (0.53) | IMPDH2BRD4ALDH1A1KDM4ENPC1 | |
| SCHEMBL17067737 | 0.80 | SCN9A (0.52) | IMPDH2BRD4ALDH1A1KDM4ENPC1 | |
| SCHEMBL4847619 | 0.80 | IMPDH2 (0.55) | IMPDH2ALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL12260497 | 0.79 | IMPDH2 (0.50) | IMPDH2BRD4ALDH1A1KDM4ENPC1 | |
| SCHEMBL15712173 | 0.78 | BRD4 (0.51) | IMPDH2BRD4ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103709171-B | There is the pyridazine also derivative of [3,4-b] indole framework structure and synthetic method thereof | WUHAN UNIVERSITY (CN) | 2015-09-16 | — | — | CN | claimed |
| US-20230165131-A1 | LIGHT EMITTING ELEMENT | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-05-25 | — | — | US | disclosed |
| EP-3647392-B1 | LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT | KYULUX INC (JP) | 2021-09-08 | — | — | EP | disclosed |
| US-20200157076-A1 | ACLY INHIBITORS AND USES THEREOF | NIMBUS DISCOVERY, INC. | 2020-05-21 | — | — | US | disclosed |
| US-20190252625-A1 | ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR | KYULUX, INC. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-10276803-B2 | Organic light-emitting device, and light-emitting material and compound used therefor | KYULUX, INC. (JP) | 2019-04-30 | — | — | US | disclosed |
| US-20170256720-A1 | ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR | KYULUX, INC. (JP) | 2017-09-07 | — | — | US | disclosed |
| US-20170256720-A1 | ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR | KYULUX, INC. (JP) | 2017-09-07 | — | — | US | disclosed |
| US-9502668-B2 | Organic light-emitting device, and light-emitting material and compound used therefor | KYULUX, INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9502668-B2 | Organic light-emitting device, and light-emitting material and compound used therefor | KYULUX, INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-6277519-B1 | QUENCHING AN ALLOY MELT; COMMINUTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6096144-A | TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5858571-A | TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| CN-1006386-B | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | SHINETSU CHEM IND CO (JP) | 1990-01-10 | — | — | CN | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| CN-85107531-A | Process for producing vinyl chloride polymer | — | 1987-01-21 | — | — | CN | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157076-A1 | ACLY INHIBITORS AND USES THEREOF | ACLY, ATP5ME, ATP5MG | IMPDH2 983/4885BRD4 3711/4885ALDH1A1 1455/4885 |
| US-10276803-B2 | Organic light-emitting device, and light-emitting material and compound used therefor | CRY1, WEE1, OR51E2 | IMPDH2 1108/4885BRD4 1409/4885ALDH1A1 80/4885 |
| US-20170256720-A1 | ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR | CRY1, WEE1, OR51E2 | IMPDH2 1108/4885BRD4 1409/4885ALDH1A1 80/4885 |
| US-20190252625-A1 | ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR | CRY1, WEE1, OR51E2 | IMPDH2 1108/4885BRD4 1409/4885ALDH1A1 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.